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Lidocaine and phenytoin- both are sodium channel blockers. Lidocaine is a local anaesthetic and an anti-arrhythmic. Phenytoin is an anticonvulsant. What explains their differential action? Is it because of their difference in pharmacokinetics.
Drugs, more than often, have multiple actions. The ability of drugs to interact with different targets and sometimes same target in differe...
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Dose-response curve is graphed by plotting the response obtained against incremental doses of the administered drug. Dose response is of t...
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Drugs, more than often, have multiple actions. The ability of drugs to interact with different targets and sometimes same target in differe...
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The direct effect of cocaine on the vagal centre in the brain can cause bradycardia, but the bradycardia is seldom seen clinically. At the ...
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