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Lidocaine and phenytoin- both are sodium channel blockers. Lidocaine is a local anaesthetic and an anti-arrhythmic. Phenytoin is an anticonvulsant. What explains their differential action? Is it because of their difference in pharmacokinetics.
Drugs, more than often, have multiple actions. The ability of drugs to interact with different targets and sometimes same target in differe...
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Acute mountain sickness is triggered by low oxygen at high altitudes. The ensuing hypoxia leads to adaptive changes by the human body. In t...
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Dose-response curve is graphed by plotting the response obtained against incremental doses of the administered drug. Dose response is of t...
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REDISTRIBUTION The phenomenon of redistribution is seen with drugs which are highly lipid soluble. After drug administration, when the dru...
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